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Tox Tuesday's - July

Our #ToxTuesday posts from July. The horses likely became ill after eating hay that was contaminated with the toxin-producing bacteria Clostridium botulinum. The bacteria exists in the soil & in decaying animal carcasses where it...    »

Tox Tuesday's - June

Our #ToxTuesday posts from June. Xylitol (sugar substitute) causes a rapid release in insulin in dogs (but not humans), which may result in life-threatening rapid hypoglycemia #ToxTuesday— INDS, Inc. (@INDSInc) June 12, 2018 This...    »

Tox Tuesday's - May

Our #ToxTuesday posts from May A study at the University of Cambridge looked at over 100 genes necessary for embryo survival in mice, over two thirds of these genes were associated with the placenta #ToxTuesday...    »

Tox Tuesday's - April

Our #ToxTuesday posts from April Nemertides (small toxic proteins) are a new family of toxins identified in the mucus that coats Bootlace worms #ToxTuesday— INDS, Inc. (@INDSInc) April 3, 2018 Really interesting study in...    »

Tox Tuesday's - March

Our #ToxTuesday posts from March A component of scorpion venom, iberiotoxin, reduces the severity of Rheumatoid arthritis in animal models by blocking a potassium channel specific to fibroblast-like synviocytes (cells that play a major role...    »

Tox Tuesday's - February

In case you missed them. An interesting new article finds that Bacterioides fragilis toxin induces a pro-carcinogenic signaling relay from the colonic epithelial cells to a mucosal Th17 response that results in myeloid-cell-dependent distal colon...    »

FDA Clears Oricula Therapeutics Investigational New Drug Application for Clinical Trials

ORC-13661 Could Be the First Medicine Approved Specifically to Prevent Hearing Loss of Patients Using Certain Antibiotics Press Release (PDF)     »

Joyce Zandee of INDS Inc to Speak at Society of Toxicology 56th Annual Meeting

Joyce Zandee, program manager for the INDS Inc. SEND Explorer® development team, will be part of the MPI Research Exhibitor-Hosted Session at the 56th Annual Society of Toxicology Meeting in Baltimore, Maryland. The session is...    »

A New Way to Define Proarrhythmic Risk? Exploring Human Induced Pluripotent Stem-Cell Derived Cardiomyocytes

by Krista K Greenwood, PhD Originally posted on Society of Toxicology’s Communiqué Blog Attrition of novel drug candidates due to cardiovascular liabilities (including proarrhythmic risk due to delayed ventricular repolarization and Torsades-de-Pointes arrhythmia) remains a...    »

Instem to be Exclusive Global Supplier of SEND Explorer®

Instem Expands SEND Suite with Data Visualization and Analysis Solution Instem Signs Agreement with Integrated Nonclinical Development Solutions, Inc.; Becomes Exclusive Global Supplier of SEND Explorer® CONSHOHOCKEN, PA - (BUSINESS WIRE) – July 29, 2016...    »